Sarecycline is a unique drug that was approved for the treatment of skin conditions. The doctors note that this is the first case in the past 40 years. The Yale researchers have explained the unique chemical structure that makes it so effective. The new study focuses on the biological analysis of a series of tetracycline drugs that are used to treat acne.
Sarecycline has the ability to bind to RNA protein formations inside the cell. It provides the code for making specific proteins in bacterial ribosomes. Ribosomes, in turn, present in all living cells, bind amino acids.
Like other tetracycline drugs, sarecycline actively treats rashes on the skin, suppressing the synthesis of bacterial protein. In the pathogenic bacteria that causes acne, they block the functional ability of the ribosomes.
Christopher Bunick, an assistant professor of dermatology at Yale University, noted that he and his colleagues observe the high structural importance of seracycline. The scientists have never seen such a method before in this class of antibiotics.
He suggests that sarecycline has special unique properties among the tetracyclines class. The scientists were able to explain the low profile of drug resistance that significantly increases the effectiveness of the drug.
By upsetting the state of the ribosome protein, seracycline protects cells from outside bacterial interference. During the study the scientists were able to prove that compounds of tetracycline antibiotics can be used to develop a highly effective antibiotic.