Fat Stores in Cells Help to Fight Bacteria: A New Tactic for Winning Infections

Fat stores in cells help fight bacteria

Fat is part of the cell's arsenal that contains toxic proteins designed to fight bacteria. The human body is capable of using many different tactics to combat bacteria. But the scientists identified another weapon. These are tiny droplets of fat that are filled with toxic proteins that kill bacteria. Complex organisms are composed of eukaryotic cells, which, in turn, contain subcellular structures, that is called organelles.

They all work together and thus provide cell functionality. In this case, the cell's brain is the nucleus, and lipid droplets accumulate fuel that can be supplied to the cell if it is necessary. These droplets attach to the mitochondria, it generates most of the generated energy.

The studies have shown that some viruses and bacteria can use these drops to grow on their own. And until a certain point, the scientists were convinced that the fat droplets supported the infection.

Robert Parton, who is a researcher from the University of Queensland in Australia found that microbial exposure to fruit flies causes lipid droplets to form with antimicrobial activity. The scientists decided to find out if this strange fighting technique works in mammalian cells.

Lipopolysaccharide was introduced into the body of mice. It is a special toxin that is produced by viral bacteria. He began to stimulate cells in the liver of mice to produce lipid droplets and increase their size.

Those cells that were infected with the toxin, as a result, "packed" hundreds of antiviral and antibacterial proteins and, having separated from mitochondria, they began to move to the bacterial toxin, destroying it.

This is a completely new way that cells can defend themselves on their own with the help of fats, the scientists have called a hidden weapon that requires additional study in the fight against infections that enter the body.