Cancer gene activation helps repair damaged heart muscle

Cancer gene activation helps repair damaged heart muscle

An amazing feature of the cancer gene was discovered by scientists. It turns out that its activation improves the regeneration of damaged heart muscle. Heart diseases fall into two categories. These are those that were acquired at birth and those that are considered acquired damage to the heart muscle. Both categories are causes of death in most European countries.

The heart muscle can be damaged in various cases. For example, due to a lack of oxygen, as in coronary disease, or due to stressful situations and tension, which leads to illness. There is no way in the world to repair damaged and dead cells of the heart muscle.

The scars formed on it are tightened, but the heart partially loses its ability to contract, and the body as a whole becomes weaker due to a lack of oxygen saturation. As a result, this leads to a serious deterioration in the quality of life in death. Worldwide, 23 million people suffer from it every year.

During a heart attack, when one or more arteries of the heart muscle are blocked, up to one billion contractile fibres of the heart muscle are lost, scars form and a person’s life becomes in danger. The heart cannot heal itself and scientists are looking for ways to do this artificially.

They found a way to stimulate the heart to self-healing. University of Cambridge conduct research using laboratory mice. Like all mammals, their cells multiply, which causes the growth of organs and the whole body. The mechanism of such replication is contained in the cell cycle.

But in this process, incorrect replication of genetic DNA can occur, which can lead to the appearance of a cancerous tumour. In the experiment with mice, the researchers observed a strange sequence - the increasing activity of this gene led to the appearance of cancer.

Stimulating effects were caused by the replication of a huge number of cells. But in this case, completely different changes took place in the heart. Gene activity caused the effect of restoration of heart muscle cells, Cyclin T1 protein helped. This method may become a new treatment for heart disease.